Bleeding disorders: dental considerations Acquired or congenital bleeding disorders of dental treatment concern include haemophilia, von Willebrand disease, other factor deficiencies and thrombocytopenia. Some systemic conditions also interfere with haemostasis, such as kidney, liver and bone marrow disorders. Patients with bleeding disorders should be managed in a specialist setting, with appropriate consultation with the patient’s specialist or multidisciplinary team. Bleeding Disorders haemophilia von Willebrand disease Other factor deficiencies  thrombocytopenia Causes Bleeding disorder may be due to defect in platelet activation, function and contact activation.  It may also be due to defect in clotting proteins or antithrombin function.  The commonest caused of bleeding disorder are  warfarin von Willebrand disease aspirin Warfarin is the commonest anticoagulant that interferes by preventing the production of clotting factors by blocking vitamin K. von W...